FLO-ELA

Fluid Optimisation in Emergency Laparotomy (FLO-ELA)

Open-label, multicentre, randomised controlled trial of cardiac output-guided haemodynamic therapy compared to usual care in patients undergoing emergency bowel surgery.

FLO-ELA is a large pragmatic trial to evaluate the clinical effectiveness of peri-operative cardiac output guided haemodynamic therapy in patients aged 50 years and over undergoing major emergency bowel surgery. We will compare this treatment to usual clinical care in 7646 patients across 100 UK hospitals.


  • Chief Investigator: Dr Mark Edwards, University of Southampton
  • Interested in this trial? Contact us.